Frequency of Upper Airway Symptoms before and during Continuous Positive Airway Pressure Treatment in Patients with Obstructive Sleep Apnea Syndrome

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Background: Upper airway side effects are common during nasal continuous positive airway pressure (nCPAP) treatment and may affect the use of nCPAP. Objectives: It was our aim to evaluate the prevalence of upper airway symptoms in obstructive sleep apnea syndrome (OSAS) patients before and during nCPAP treatment and to assess the possible association between the symptoms and long-term adherence to the treatment. Methods: We examined 385 consecutive OSAS patients (79% men, mean age 8 SD 52 8 10 years and apnea-hypopnea index 33 8 23) by means of a prospective questionnaire-based survey. The patients filled in questionnaires about upper airway symptoms before starting nCPAP and after 2 months of treatment. Results: Upper airway symptoms were common before starting nCPAP: 61% of the patients reported dryness of mouth, 54% dryness of throat, 52% nasal stuffiness, 51% dryness of nose, 30% sneezing, 24% mucus in throat, 17% rhinorrhea, and 6% nose bleeds daily or almost daily. In CPAP users there was a significant decline in the number of patients with frequent mouth Received: March 25, 2010 Accepted after revision: July 12, 2010 Published online: September 28, 2010 Hanna-Riikka Kreivi, MD Division of Pulmonary Diseases Department of Medicine, Helsinki University Central Hospital Haartmaninkatu 4, PO Box 340, FI–00290 Helsinki (Finland) Tel. +358 9 4711, Fax +358 9 4717 4481, E-Mail hanna-riikka.kreivi @ fimnet.fi © 2010 S. Karger AG, Basel 0025–7931/10/0806–0488$26.00/0 Accessible online at: www.karger.com/res D ow nl oa de d by : 54 .1 91 .4 0. 80 4 /3 0/ 20 17 6 :5 1: 54 P M

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Frequency of upper airway symptoms before and during continuous positive airway pressure treatment in patients with obstructive sleep apnea syndrome.

BACKGROUND Upper airway side effects are common during nasal continuous positive airway pressure (nCPAP) treatment and may affect the use of nCPAP. OBJECTIVES It was our aim to evaluate the prevalence of upper airway symptoms in obstructive sleep apnea syndrome (OSAS) patients before and during nCPAP treatment and to assess the possible association between the symptoms and long-term adherence...

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تاریخ انتشار 2010